Gene and the remaining humans flee the predators that chase them at night. One of these is Ashley June, the girl he left behind. When the group joins a band of humans living in the mountains, they face a new danger. As enemies push Gene and Sissy closer, Gene makes a critical discovery.

In 1935, ten-year-old Alex Maki of Bainbridge Island, Washington, is horrified to discover that his new pen pal, Charlie Lévy of Paris, France, is a girl, but in spite of his initial reluctance, their letters continue over the years and they fight for their friendship even as Charlie endures the Nazi occupation and Alex leaves his family in an internment camp and joins the Army.

Teenage Gene and a group of human survivors flee from the vampire predators that have become the majority and find refuge among a group of humans living high in the mountains, but their society may be just as evil as the one they fled from.